Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/41245
DC FieldValueLanguage
dc.contributor.authorChiu, H.C.en_US
dc.contributor.author邱信程zh_TW
dc.contributor.authorWu, A.T.en_US
dc.contributor.authorLin, Y.F.en_US
dc.date2001zh_TW
dc.date.accessioned2014-06-06T08:05:12Z-
dc.date.available2014-06-06T08:05:12Z-
dc.identifier.issn0032-3861zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/41245-
dc.description.abstractpH-Sensitive dextran hydrogels were prepared by free radical polymerization of methacrylate derivatized dextran, acrylic acid and N-t-butylacrylamide. Incorporation of acrylic acid in hydrogels was confirmed by Fourier transform infrared spectroscopy. The pH-dependent swelling of hydrogels was strongly influenced by the acrylic acid content, conjugation degree of methacrylate moiety with dextran and modified dextran concentration. Intermolecular polymerization that occurred to a greater extent with a lower degree of conjugation of methacrylate and/or higher concentration of modified dextran effectively increased the network density of hydrogels. An increase of acrylic acid reduced the enzymatic degradability of pre-swollen hydrogels by dextranase, although the increased equilibrium swelling was observed. (C) 2000 Elsevier Science Ltd. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationPolymeren_US
dc.relation.ispartofseriesPolymer, Volume 42, Issue 4, Page(s) 1471-1479.en_US
dc.relation.urihttp://dx.doi.org/10.1016/s0032-3861(00)00523-1en_US
dc.subjectdextran hydrogelsen_US
dc.subjectpH-dependent swellingen_US
dc.subjectenzymatic degradabilityen_US
dc.subjectph-sensitive hydrogelsen_US
dc.subjectcontrolled-releaseen_US
dc.subjectenzymatic degradationen_US
dc.subjectglycidyl methacrylateen_US
dc.subjectdrug-deliveryen_US
dc.subjectpoly(ethylene glycol)en_US
dc.subjectmodelen_US
dc.subjectproteinen_US
dc.subjectcross-linkingen_US
dc.subjectin-vitroen_US
dc.subjectmicrospheresen_US
dc.titleSynthesis and characterization of acrylic acid-containing dextran hydrogelsen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/s0032-3861(00)00523-1zh_TW
item.fulltextno fulltext-
item.languageiso639-1en_US-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
Appears in Collections:化學工程學系所
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