Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/41435
DC FieldValueLanguage
dc.contributor.authorHsu, S.H.en_US
dc.contributor.author徐善慧zh_TW
dc.contributor.authorChen, J.Y.en_US
dc.date1999zh_TW
dc.date.accessioned2014-06-06T08:05:31Z-
dc.date.available2014-06-06T08:05:31Z-
dc.identifier.issn0141-3910zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/41435-
dc.description.abstract2-Butene-1,4-diol was used as the chain extender in poly(ether)urethane (PEU) synthesis. The carbon-carbon double bonds introduced are presumed to serve as scavengers for free radicals that are generally believed to cause oxidative biodegradation. Two categories of PEU, one chain extended with 1,4-butanediol and the other chain extended with 2-butene-1,4-diol, were synthesized by a general two-stage polymerization method. Biostability was tested in an in vitro accelerated environment. The degradative effect was examined by optical microscopy combined with a self-designed image analysis program, as well as by attenuated total reflectance infrared spectroscopy. Blood compatibility was evaluated by a platelet adhesion index (RIPA). It was found that PEU using 2-butene-1,4-diol as chain extender showed less surface degradation in the biostability test. Platelet adhesion was similar for all PEU. Results indicated that using butenediol in PEU synthesis could enhance the biostability of the product without impairing its blood compatibility. (C) 1999 Elsevier Science Ltd. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationPolymer Degradation and Stabilityen_US
dc.relation.ispartofseriesPolymer Degradation and Stability, Volume 65, Issue 3, Page(s) 341-345.en_US
dc.relation.urihttp://dx.doi.org/10.1016/s0141-3910(98)00219-5en_US
dc.subjectsubcutaneous implantationen_US
dc.subjectsegmented polyurethanesen_US
dc.subjectpolymer degradationen_US
dc.subjectpolyetherurethaneen_US
dc.subjectmechanismsen_US
dc.subjectchemistryen_US
dc.subjectelastomeren_US
dc.subjectdevicesen_US
dc.subjectratsen_US
dc.titleEnhanced biostability by using butenediol as chain extenders in the synthesis of poly(ether)urethanesen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/s0141-3910(98)00219-5zh_TW
item.grantfulltextnone-
item.openairetypeJournal Article-
item.languageiso639-1en_US-
item.fulltextno fulltext-
item.cerifentitytypePublications-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
Appears in Collections:化學工程學系所
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