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|標題:||Cell migration rate on poly(epsilon-caprolactone)/poly(ethylene glycol) diblock copolymers and correlation with the material sliding angle||作者:||Hsu, S.H.
|關鍵字:||cell migration;microphase separation;nanotopography;PCL/PEG diblock;copolymer;sliding angle;colloidal lithography;fibroblast adhesion;polymer;nanotopography;morphology||Project:||Macromolecular Bioscience||期刊/報告no：:||Macromolecular Bioscience, Volume 7, Issue 4, Page(s) 482-490.||摘要:||
The nanostructure of a biomaterial surface has strong influence on cell behavior. The migration of cells on nanostructured surfaces, however, has not been investigated so far. In this study, we used PCL/PEG diblock copolymers as model surfaces to examine the effect of nanoislands on migration of different cells, including fibroblasts and endothelial cells. The water sliding angle of the substrates was measured. The cell migration rate was examined under a real-time optical microscope. It was found that a greater cell migration rate correlated with the smaller sliding angle of the substrate.
|Appears in Collections:||化學工程學系所|
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