Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/41617
標題: Cell migration rate on poly(epsilon-caprolactone)/poly(ethylene glycol) diblock copolymers and correlation with the material sliding angle
作者: Hsu, S.H.
徐善慧
Tang, C.M.
Chiu, J.J.
Liao, T.C.
Lin, C.C.
Iwata, H.
林助傑
關鍵字: cell migration;microphase separation;nanotopography;PCL/PEG diblock;copolymer;sliding angle;colloidal lithography;fibroblast adhesion;polymer;nanotopography;morphology
Project: Macromolecular Bioscience
期刊/報告no:: Macromolecular Bioscience, Volume 7, Issue 4, Page(s) 482-490.
摘要: 
The nanostructure of a biomaterial surface has strong influence on cell behavior. The migration of cells on nanostructured surfaces, however, has not been investigated so far. In this study, we used PCL/PEG diblock copolymers as model surfaces to examine the effect of nanoislands on migration of different cells, including fibroblasts and endothelial cells. The water sliding angle of the substrates was measured. The cell migration rate was examined under a real-time optical microscope. It was found that a greater cell migration rate correlated with the smaller sliding angle of the substrate.
URI: http://hdl.handle.net/11455/41617
ISSN: 1616-5187
DOI: 10.1002/mabi.200600248
Appears in Collections:化學工程學系所

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