Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/43229
標題: Demonstration of continuous supercritical carbon dioxide anti-solvent purification and classification of nano/micro-sized precipitates of algal zeaxanthin from Nannochloropsis oculata
作者: Chen, P.Y.
張傑明
Shen, C.T.
Liau, B.C.
Lee, T.M.
Wu, T.M.
Shieh, C.J.
Chang, C.M.J.
吳宗明
關鍵字: Nannochloropsis oculata;Zeaxanthin;Nano- or micro-sized particles;Supercritical anti-solvent recrystallization;macular degeneration;beta-carotene;brazilian propolis;photoprotection;co2;extraction;particles;fluids;plants;acid
Project: Journal of the Taiwan Institute of Chemical Engineers
期刊/報告no:: Journal of the Taiwan Institute of Chemical Engineers, Volume 42, Issue 4, Page(s) 598-603.
摘要: 
This study examined time dependent continuous supercritical anti-solvent (SAS) recrystallization applied for purifying and generating zeaxanthin rich particulates from micro-algal Nannochloropsis oculata. Feed solutions varied from 0.4 to 1.2 mg/ml subjected into a 250 ml SAS crystallizer to yield a few classifications of nano- or micro-sized purified precipitates corresponding to different recrystallization time zones. The effect of operational conditions on amount, recovery of the zeaxanthin and mean size, morphology of the precipitates was obtained from experimentally designed SAS process. The mean size of particles falls within several hundreds of nanometers and the content of zeaxanthin in the particulates range from 65 to 71%, which relies highly upon the recrystallization time. This work demonstrated an environmental benign process in producing nano- or micro-sized particles containing rich-zeaxanthin from algal solution by using supercritical anti-solvent within minutes. (C) 2010 Taiwan Institute of Chemical Engineers. Published by Elsevier B.V. All rights reserved.
URI: http://hdl.handle.net/11455/43229
ISSN: 1876-1070
DOI: 10.1016/j.jtice.2010.11.011
Appears in Collections:材料科學與工程學系

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