Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/43240
標題: Preparation and characterization of thermosensitive polymers grafted onto silica-coated iron oxide nanoparticles
作者: Lien, Y.H.
吳宗明
Wu, T.M.
關鍵字: core-shell structure;magnetic nanoparticles;superparamagnetism;multifunctional;thermosensitive;magnetite nanoparticles;biomedical applications;n-isopropylacrylamide;colloidal silica;delivery-system;drug-delivery;microspheres;nanocomposites;surface;microemulsion
Project: Journal of Colloid and Interface Science
期刊/報告no:: Journal of Colloid and Interface Science, Volume 326, Issue 2, Page(s) 517-521.
摘要: 
In this study, multifunctional nanoparticles containing thermosensitive polymers grafted onto the surfaces of 6-nm monodisperse Fe(3)O(4) magnetic nanoparticles coated by silica were synthesized using reverse microemulsions and free radical polymerization. The magnetic properties Of SiO(2)/Fe(3)O(4) nanoparticles show superparamagnetic behavior. Thermosensitive PNIPAM (poly(N-isopropylacrylamide)) was then grafted onto the surfaces Of SiO(2)/Fe(3)O(4) nanoparticles, generating thermosensitive and magnetic properties of nanocomposites. The sizes of fabricated nanoparticles with core-shell structure are controlled at about 30 nm and each nanoparticle contains only one monodisperse Fe(3)O(4) core. For thermosensitivity analysis, the phase transition temperatures of multifunctioral nanoparticles measured using DSC was at around 34-36 degrees C. The magnetic characteristics of these multifunctional nanoparticles were also superparamagnetic. (C) 2008 Elsevier Inc. All rights reserved.
URI: http://hdl.handle.net/11455/43240
ISSN: 0021-9797
DOI: 10.1016/j.jcis.2008.06.020
Appears in Collections:材料科學與工程學系

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