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標題: Analysis and measurements of mixing in pressure-driven microchannel flow
作者: Chen, J.M.
Horng, T.L.
Tan, W.Y.
關鍵字: microfluidics;non-uniform diffusion;spectral method;mixing;measurement;chaotic mixer;fabrication
Project: Microfluidics and Nanofluidics
期刊/報告no:: Microfluidics and Nanofluidics, Volume 2, Issue 6, Page(s) 455-469.
The mixing phenomena for two fluid streams in pressure-driven rectangular microchannels are analyzed and directly compared with the measurements of mixing intensity for a wide range of aspect ratio (width/depth = 1-20). In the analysis, the three-dimensional transport equation for species mixing was solved using the spectral method in a dimensionless fashion covering a large regime of the normalized downstream distance. The analysis reveals the details of non-uniform mixing process, which originates from the top and bottom walls of the channel and stretches out toward the center of the channel, and its transition to uniformity. Employing different length scales for the non-uniform and uniform mixing regimes, the growth of mixing intensity can be expressed in a simple relationship for various aspect ratios in the large range. The mixing experiments were carried out on silicon- and poly(methyl methacrylate) (PMMA)-based T-type micromixers utilizing fluids of pH indicator (in silicon channel) and fluorescent dye (in PMMA channel) to evaluate the mixing intensity based on flow visualization images. Using conventional microscopes, the experiments demonstrate the mixing intensity as a power law of the stream velocity for all the microfluidic channels tested. The variations of measured mixing intensity with the normalized downstream distance are found in favorable agreement with the numerical simulations. The comparison between the experiments and simulations tells the capabilities and limitations on the use of conventional microscopes to measure the mixing performance.
ISSN: 1613-4982
DOI: 10.1007/s10404-006-0092-9
Appears in Collections:機械工程學系所

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