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標題: Triplex-pumping CD-like microfluidic platform with parabolic microchannels
作者: Wang, G.J.
Chang, C.H.
Yang, H.
關鍵字: capillary-electrophoresis;centrifugal;separation;systems
Project: Microsystem Technologies-Micro-and Nanosystems-Information Storage and Processing Systems
期刊/報告no:: Microsystem Technologies-Micro-and Nanosystems-Information Storage and Processing Systems, Volume 12, Issue 10-11, Page(s) 899-905.
In this research, we propose a triplex-pumping CD-like multi-channel electrophoresis-based biomedical separation system that is driven by the interactions of the centrifugal force, the electric field force, and the Coriolis force. In this novel platform,the heat-conduction theory is implemented to formulate the relations between the sample velocity and the dimensions of the microchannel. The parabola microchannel that has the least friction force under triplex-pumping forces is determined by computer simulations. The centrifugal force control of this system is realized by the angular velocity of a DC servo motor, while the electric field is governed through multi-stage potential circuits, which are suitably designed and fabricated by sputtering using the metal mask method, and can be adjusted to provide multi-stage voltages. Experimental results demonstrated that the proposed parabola microchannels can effectively eliminate the effects of friction force.
ISSN: 0946-7076
DOI: 10.1007/s00542-006-0120-4
Appears in Collections:生醫工程研究所

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