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|標題:||Mimicry of molecular pretenders The terminal structures of satellites associated with plant RNA viruses||作者:||Huang, Y.W.
|關鍵字:||satellite RNA;satellite virus;plant RNA virus;RNA terminal structure;molecular mimicry;cucumber mosaic-virus;turnip-crinkle-virus;tobacco necrosis virus;complete nucleotide-sequence;viral replication repressor;yellow dwarf;virus;helper virus;secondary structure;capsid protein;3'-untranslated region||Project:||Rna Biology||期刊/報告no：:||Rna Biology, Volume 7, Issue 2, Page(s) 162-171.||摘要:||
Satellite RNAs (satRNAs) and satellite viruses depend on the replicase complexes provided by their cognate helper viruses and host plants for replication, pretending that they are part of the viral genomes. Although satRNAs and satellite viruses do not share significant nucleotide sequence similarity with the helper viruses, the essential cis-acting elements recognized by the replicase complexes must reside on their genomes, acting as the mimicry for the molecular pretenders. By understanding how this molecular mimicry deceives the helper viruses into supporting the satellites, a significant amount of knowledge of the basic requirements and mechanisms for replication of viruses and satellites has been obtained. Here we review the recent advances in understanding the effects of the cis elements at the termini of satRNAs and satellite viruses on their accumulation. Several well-characterized satellite/helper virus systems, representing the non-coding short satRNAs, mRNA-type long satRNAs, circular satRNAs and satellite viruses, are compared and contrasted. It is concluded that different satellites may adopt different strategies to exploit the replication/transcription/translation machineries of their helper viruses, and different mimicries may be implemented by the same molecular pretender for different biological functions.
|Appears in Collections:||生物科技學研究所|
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