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|標題:||Visible-light-induced bactericidal activity of a nitrogen-doped titanium photocatalyst against human pathogens||作者:||Wong, M.S.
|關鍵字:||acute respiratory syndrome;molecular epidemiology;streptococcus-pyogenes;antibiotic-resistance;superoxide-dismutase;oxide films;coronavirus;taiwan;virulence;tio2||Project:||Applied and Environmental Microbiology||期刊/報告no：:||Applied and Environmental Microbiology, Volume 72, Issue 9, Page(s) 6111-6116.||摘要:||
The antibacterial activity of photocatalytic titanium dioxide (TiO2) substrates is induced primarily by UV light irradiation. Recently, nitrogen- and carbon-doped TiO2 substrates were shown to exhibit photocatalytic activities under visible-light illumination. Their antibacterial activity, however, remains to be quantified. In this study, we demonstrated that nitrogen-doped TiO2 substrates have superior visible-light-induced bactericidal activity against Escherichia coli compared to pure TiO2 and carbon-doped TiO2 substrates. We also found that protein- and light-absorbing contaminants partially reduce the bactericidal activity of nitrogen-doped TiO2 substrates due to their light-shielding effects. In the pathogen-killing experiment, a significantly higher proportion of all tested pathogens, including Shigella flexneri, Listeria monocytogenes, Vibrio parahaemolyticus, Staphylococcus aureus, Streptococcus pyogenes, and Acinelobacter baumannii, were killed by visible-light-illuminated nitrogen-doped TiO2 substrates than by pure TiO2 substrates. These findings suggest that nitrogen-doped TiO2 has potential application in the development of alternative disinfectants for environmental and medical usages.
|Appears in Collections:||分子生物學研究所|
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