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標題: Antimicrobial activity and cytotoxicity of the essential oil of Curcuma zedoaria
作者: 毛正倫
Lai, E.Y.C.
Chyau, C.C.
Mau, J.L.
Chen, C.C.
Lai, Y.J.
Shih, C.F.
Lin, L.L.
關鍵字: Curcuma zedoaria;essential oil;antimicrobial activity;Vibrio;parahaemolyticus;cytotoxicity;antioxidant activity;extracts;sesquiterpenes;curcuminoids;antitumor;liver;line
Project: American Journal of Chinese Medicine
期刊/報告no:: American Journal of Chinese Medicine, Volume 32, Issue 2, Page(s) 281-290.
The chemical compositions of the essential oil of Curcuma zedoaria (Berg.) Rosc. were analyzed by gas chromatography-mass spectrometry (GC-MS) and showed a high content of epicurzerenone and curdione representing 46.6% and 13.7% of the total oil, respectively. The essential oil was evaluated for potential antimicrobial activity against Staphylococcus aureus, Escherichia coli, Pseudomonasa aeruginosa, Vibrio parahaemolyticus, Salmonella typhimurium and Bacillus cereus. V parahaemolyticus was sensitive to the presence of the essential oil, while the most resistant strain appeared to be E. coli. Based on 3(4,5-dimethylthiazol-2-yl)-2, 5-diphenyl-tetrazolium bromide (MTT) assay, nitroblue tetrazolium (NBT) reduction and cell morphology, the essential oil of C zedoaria could inhibit the proliferation of human promyelocytic leukemia HL-60 cells. These results suggest that the essential oil has the antimicrobial activity against some of Gram-positive and negative pathogenic microorganisms and the components of the extract lead to the apoptosis of human cancer cell line.
ISSN: 0192-415X
DOI: 10.1142/s0192415x0400193x
Appears in Collections:食品暨應用生物科技學系

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