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標題: Action of methanolic extract of mung bean hulls as inhibitors of lipid peroxidation and non-lipid oxidative damage
作者: Duh, P.D.
Du, P.C.
Yen, G.C.
關鍵字: methanolic extract of mung bean hulls;antioxidant effect;phospholipid;deoxyribose;protein;deoxyguanosine;hydroxyl radical;lipid;peroxidation;oxidative damage;hydroxyl radicals;antioxidant activity;ascorbic-acid;deoxyribose;toxicity;protein;systems;liver;tea
Project: Food and Chemical Toxicology
期刊/報告no:: Food and Chemical Toxicology, Volume 37, Issue 11, Page(s) 1055-1061.
The antioxidant effects of methanolic extract of mung bean hulls (MEMBH) on lipids and non-lipids, including liposome, carbohydrate, protein and 2'-deoxyguanosine (2'-dG), were investigated. MEMBH exhibited a remarkable antioxidant effect in a liposome model system, indicating that the extract was an inhibitor of lipid peroxidation. The inhibitory effect of MEMBH on deoxyribose damage was amount-dependent and it afforded considerable protection against damage to deoxyribose. fn addition, MEMBH at low amounts was more effective in protecting protein oxidation. Furthermore, the oxidation of 2'-dG to 8-hydroxy-2'-deoxyguanosine (8-OH-2'dG) was inhibited by MEMBH. These results show that the extract also was an inhibitor of non-lipid oxidation damage. The extract exhibited metal binding ability and scavenging activity for hydrogen peroxide and hydroxyl radical, which may explain the mechanism of their protecting lipids and non-lipids from oxidative damage. (C) 1999 Elsevier Science Ltd. All rights reserved.
ISSN: 0278-6915
DOI: 10.1016/s0278-6915(99)00096-4
Appears in Collections:食品暨應用生物科技學系

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