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|標題:||Evaluation and application of conducting polymer entrapment on quartz crystal microbalance in flow injection immunoassay||作者:||Liu, Y.C.
|關鍵字:||quartz crystal microbalance;flow-injection-analysis;conducting polymer;entrapment;pseudorabies virus;point-of-care testing;glucose-oxidase;immobilization;biosensors;immunosensors;polypyrrole;disease;virus;films||Project:||Biosensors & Bioelectronics||期刊/報告no：:||Biosensors & Bioelectronics, Volume 18, Issue 7, Page(s) 937-942.||摘要:||
An immunosensor employing conducting polymer entrapment (CPE) method to immobilize immuno-protein on the quartz crystal microbalance (QCM) for clinical flow-injection-analysis (FIA) purpose was exploited. By comparing the CPE approach and the conventional physical immobilization (PI) method, a frequency shift of the former was 47% higher than that of the latter when measuring at 0.5 mg/ml human serum albumin antibody concentration. This implied that CPE was a feasible approach for developing QCM-FIA process. An immunoassay of anti-pseudorabies virus antibody in mouse sera further exemplified its practical potential in diagnostic implication. (C) 2002 Elsevier Science B.V. All rights reserved.
|Appears in Collections:||微生物暨公共衛生學研究所|
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