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標題: Newcastle disease virus isolated from recent outbreaks in Taiwan phylogenetically related, to viruses (genotype VII) from recent outbreaks in western Europe
作者: Yang, C.Y.
Shieh, H.K.
Lin, Y.L.
Chang, P.C.
關鍵字: Newcastle disease virus;fusion protein;nucleotide sequence;epidemiology;RT-PCR;pigeon pmv-1 viruses;nucleotide-sequence;gene;pathogenicity;evolution;strains
Project: Avian Diseases
期刊/報告no:: Avian Diseases, Volume 43, Issue 1, Page(s) 125-130.
Three major outbreaks of Newcastle disease (ND) occurred in Taiwan in the last three decades (in 1969, 1984, and 1995). Newcastle disease viruses (NDVs) isolated in the three outbreaks, together with those isolated in 1998, were sequenced between nucleotides 47 and 435 of the fusion gene. A phylogenetic tree based on sequences obtained showed that the NDV isolated in 1969 was similar to the genotype III viruses. In contrast, all isolates in 1984 and seven of the eight isolates in 1995, together with all isolates in 1998, fell into the genotype VII. These results suggest chat the 1969 outbreak of ND in Taiwan was caused by the genotype III virus, whereas the 1984 and 1995 outbreaks were caused by the genotype VII viruses. To date, the genotype VII viruses have caused many outbreaks in east Asia and western Europe. We suspect that these outbreaks have constituted the fourth panzootic of ND, which is distinct from the third panzootic caused by the "pigeon PMV-1 viruses." NDV isolated in Taiwan in 1984 was the earliest isolation of the genotype VII virus.
ISSN: 0005-2086
DOI: 10.2307/1592771
Appears in Collections:微生物暨公共衛生學研究所

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