Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/67972
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dc.contributor.authorHsu, S.H.en_US
dc.contributor.authorWang, M.C.en_US
dc.contributor.authorLin, J.J.en_US
dc.date2012zh_TW
dc.date.accessioned2014-06-11T05:56:02Z-
dc.date.available2014-06-11T05:56:02Z-
dc.identifier.issn0169-1317zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/67972-
dc.description.abstractDelaminated montmorillonite particles (DMtP) are novel two-dimensional nanomaterials. Chitosan (CS) is a biodegradable polysaccharide with good biocompatibility. New nanocomposites of CS and 10-10(4) ppm of DMtP were prepared. The good dispersion of DMtP in the CS matrix was probably a result of the charge interaction between the two components. The nanocomposites demonstrated better dynamic mechanical moduli. DMtP were found to be enriched on the surface of the nanocomposites when the amount of DMtP was >10(3) ppm. This was accompanied by a decrease of the contact angle. The proliferation of fibroblasts on DMtP/CS 10(3) ppm was significantly greater than on other materials. The antimicrobial activity was enhanced markedly with the increased amount of DMtP in DMtP/CS. The inflammatory responses of DMtP in vitro and in subcutaneous rats were not obvious until the concentration of DMtP was >10(3) ppm. The biocompatibility of DMtP/CS at 10(3) ppm was even better than that of CS. The biodegradation rate of CS of the DMtP/CS nanocomposite was much faster than that of the pure CS polymer. These results suggested potential antimicrobial applications for DMtP/CS nanocomposites, especially for those containing 10(3) ppm (0.1%) of DMtP. (C) 2011 Elsevier B.V. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationApplied Clay Scienceen_US
dc.relation.ispartofseriesApplied Clay Science, Volume 56, Page(s) 53-62.en_US
dc.relation.urihttp://dx.doi.org/10.1016/j.clay.2011.09.016en_US
dc.subjectMontmorillonite (Mt)en_US
dc.subjectChitosan (CS)en_US
dc.subjectNanocompositeen_US
dc.subjectAntimicrobialen_US
dc.subjectsilver nanoparticlesen_US
dc.subjectin-vitroen_US
dc.subjectchitosanen_US
dc.subjectchitinen_US
dc.subjectexfoliationen_US
dc.subjectbiopolymeren_US
dc.subjectsystemsen_US
dc.titleBiocompatibility and antimicrobial evaluation of montmorillonite/chitosan nanocompositesen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/j.clay.2011.09.016zh_TW
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.fulltextno fulltext-
item.languageiso639-1en_US-
item.grantfulltextnone-
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