Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/68689
DC FieldValueLanguage
dc.contributor.authorChang, C.C.en_US
dc.contributor.authorYang, Y.T.en_US
dc.contributor.authorYang, J.C.en_US
dc.contributor.authorWu, H.D.en_US
dc.contributor.authorTsai, T.en_US
dc.date2008zh_TW
dc.date.accessioned2014-06-11T05:57:11Z-
dc.date.available2014-06-11T05:57:11Z-
dc.identifier.issn0143-7208zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/68689-
dc.description.abstractRose bengal is a water-soluble xanthene dye that is currently used in ophthalmology for the diagnosis of dry eyes. Although the dye is also a potential photosensitizer for photodynamic therapy of tumors, owing to insufficient lipophilicity and tumor accumulation, the clinical application of rose bengal in photodynamic therapy has been hampered, Liposomal encapsulation was seen as a promising approach to overcome these disadvantages, to-which end, the spectral properties of the dye in the presence of materials for liposome preparation were studied. The presence of phospholipid influenced the spectral properties of the dye, probably due to the establishment of an equilibrium between monomeric and dimeric forms of the dye, since the photophysical properties of rose bengal depend strongly on its environment. The liposomal encapsulation of the dye generates stronger emission than the free form of the colorant; increased lipid:dye ratio further enhances this emission. (C) 2008 Elsevier Ltd. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationDyes and Pigmentsen_US
dc.relation.ispartofseriesDyes and Pigments, Volume 79, Issue 2, Page(s) 170-175.en_US
dc.relation.urihttp://dx.doi.org/10.1016/j.dyepig.2008.02.003en_US
dc.subjectrose bengalen_US
dc.subjectliposomeen_US
dc.subjectphotosensitizeren_US
dc.subjectabsorptionen_US
dc.subjectemissionen_US
dc.subjectspectrumen_US
dc.subjectphotodynamic therapyen_US
dc.subjectporphyrinen_US
dc.subjectmembraneen_US
dc.subjectoxygenen_US
dc.subjectstateen_US
dc.titleAbsorption and emission spectral shifts of rose bengal associated with DMPC liposomesen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/j.dyepig.2008.02.003zh_TW
item.languageiso639-1en_US-
item.fulltextno fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
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