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標題: Magnolol: A multifunctional compound isolated from the Chinese medicinal plant Magnolia officinalis
作者: Chen, Y.H.
Huang, P.H.
Lin, F.Y.
Chen, W.C.
Chen, Y.L.
Yin, W.H.
Man, K.M.
Liu, P.L.
關鍵字: Antioxidant;Chinese medicine;Inflammation;Integrative medicine;Magnolol;ischemia-reperfusion injury;cholesterol-fed rabbits;bronchial-asthma;saiboku-to;smooth-muscle;in-vitro;cell-proliferation;induced;apoptosis;polymorphonuclear leukocytes;5-hydroxytryptamine release
Project: European Journal of Integrative Medicine
期刊/報告no:: European Journal of Integrative Medicine, Volume 3, Issue 4, Page(s) E311-E318.
Introduction: Chinese herbs are widely used as important remedies in Oriental integrative medicine. Magnolol is a small polyphenolic molecule with low toxicity that is isolated from the herb genus Magnolia. In preclinical experiments, magnolol was found to have anti-oxidative, anti-inflammatory, anti-tumorigenic, anti-diabetic, anti-microbial, anti-neurodegenerative and anti-depressant properties. Magnolol can also effectively regulate pain control, hormonal signalling, gastrointestinal and uterus modulation as well as provide cardiovascular and liver protective effects. Materials and methods: We briefly conducted PubMed and MEDLINE database reviews for articles that related to magnolol. Results: The major biological mechanisms of action and potential health benefits of magnolol are described. Conclusions: These health benefits of magnolol have provided an increased interest in bringing this herbal compound to the clinic as a novel therapeutic agent. Knowledge of the multiple activities of magnolol can assist with the development of magnolol derivatives and the design of clinical trials that will maximize the potential benefit of magnolol in the patient setting. (C) 2011 Published by Elsevier GmbH.Results: The major biological mechanisms of action and potential health benefits of magnolol are described.
ISSN: 1876-3820
DOI: 10.1016/j.eujim.2011.09.002
Appears in Collections:期刊論文

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