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|標題:||Nutritional factors and survival of patients with oral cancer||作者:||Liu, S.A.
|關鍵字:||nutrition;survival;oral cancer;body mass index;albumin;squamous-cell carcinoma;body-mass index;breast-cancer;neck;cavity||Project:||Head and Neck-Journal for the Sciences and Specialties of the Head and Neck||期刊/報告no：:||Head and Neck-Journal for the Sciences and Specialties of the Head and Neck, Volume 28, Issue 11, Page(s) 998-1007.||摘要:||
Background. Our objective was to determine the survival rate of patients with oral cancer who were treated at a medical center in central Taiwan. Furthermore, we attempted to investigate whether nutritional factors influence the survival. Methods. We carried out a retrospective review of 1010 chart records of patients with oral cancer. We used the Kaplan-Meier method for survival analysis and the Cox proportional hazard models to investigate the prognosticators. Results. Kaplan-Meier survival analysis showed an overall 5-year survival rate of 63.24%. The Cox proportional hazard model revealed that those with a preoperative body mass index (BMI) of < 22.8 kg/m(2) tended to have a higher probability of death (relative risk [RR] 1.292, p = .022). In addition, those with a preoperative serum albumin level of < 4.15 g/dL were generally associated with a poorer prognosis (RR = 1.313, p = .016). Conclusions. Apart from clinical features, nutritional factors also had a significant influence on the survival of patients with oral cancer, Therefore, good nutritional status is crucial for patients with oral cancer in improving their survival. (c) 2006 Wiley Periodicals, Inc.
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