Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/69027
標題: Practical synthesis of (-)-alpha-aminobenzolactam via nitration-cyclization of L-homophenylalanine ethyl ester
作者: Yu, L.T.
Huang, J.L.
Chang, C.Y.
Yang, T.K.
關鍵字: asymmetric-synthesis;inhibitors;agent
Project: Heterocycles
期刊/報告no:: Heterocycles, Volume 71, Issue 2, Page(s) 323-330.
摘要: 
A practical synthesis of chiral (-)-alpha-aminobenzolactam (2) is described. The target compound (2) was prepared from commercially available L-homophenylalanine ethyl ester hydrochloride (LHPE-HCl 1) with a highly enantiomeric purity (> 98% e.e.) by employing simple nitration and hydrogenation-cyclization reactions.
URI: http://hdl.handle.net/11455/69027
ISSN: 0385-5414
Appears in Collections:期刊論文

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