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dc.contributor.authorChang, C.W.en_US
dc.contributor.authorLin, C.C.en_US
dc.contributor.authorLien, H.Y.en_US
dc.contributor.authorLin, Y.C.en_US
dc.contributor.authorChen, Y.H.en_US
dc.contributor.authorChang, F.R.en_US
dc.contributor.authorLi, Z.H.en_US
dc.description.abstractIn this study, after doses of 1 g/kg/day of the traditional Chinese formula Ma-Xing-Shi-Gan-Tang (MXSGT), significant reversal of pneumatocysts was achieved in Spague-Dawley rats with bleomycin-induced lung fibrosis. We found that MXSGT can improve the damaged condition of general cellular membranes. Greatly increased levels of lung NO were found in the bleomycin-induced group, which were then significantly reduced by MXSGT. MXSGT drastically prevented depletion of superoxide dismutase (SOD) and reduced the myeloperoxidase (MPO) activities and malondialdehyde (MDA) levels in lung tissue of rats treated with bleomycin. On the basis of the results presented in this paper, MXSGT prevents bleomycin-induced lung fibrosis, and the mechanism may be due to the inhibitory effect on nitric oxide generation in the bleomycin-induced lung-fibrosis model of rats.en_US
dc.relationJournal of Food and Drug Analysisen_US
dc.relation.ispartofseriesJournal of Food and Drug Analysis, Volume 19, Issue 2, Page(s) 139-145.en_US
dc.titleEffects of Ma-Xing-Shi-Gan-Tang on Bleomycin- Induced Lung Fibrosis in Ratsen_US
dc.typeJournal Articlezh_TW
item.fulltextno fulltext-
item.openairetypeJournal Article-
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