Please use this identifier to cite or link to this item:
標題: Evaluation of Nanofabricated Ginseng Extract Powders
作者: Wen, H.W.
Li, W.C.
Chung, R.J.
Yin, S.Y.
Chou, T.H.
Hsieh, P.C.
Wang, P.H.
Lin, I.H.
關鍵字: Ginseng;Micro/Nano-Fabrication;Ginsenosides;Cytotoxicity Assay;Cellular Growth Enhancement;Antioxidant Capacity;performance liquid-chromatography;panax-quinquefolius l.;size;distribution;droplet size;food-science;emulsification;antioxidant;cells;microfluidization;nanotechnology
Project: Journal of Nanoscience and Nanotechnology
期刊/報告no:: Journal of Nanoscience and Nanotechnology, Volume 9, Issue 7, Page(s) 4108-4115.
The objective of this study is to investigate the nano-fabrication method for ginseng extract powders (GEPs) and detect the differences in physical and chemical properties, and cytotoxicity of GEPs before and after fabrication. White ginseng was used as the raw material to produce the GEPs (Sample A). After grinding, the GEPs passed a 40-mesh sieve (particle size < 105 mu m) and was named as Sample B. The residue (particle size > 105 mu m) was named as Sample C. Samples A and B were used for nanofabrication though the use of a high-energy ball mill. Sample B was ground for 3 hr (Sample D) and 1 hr (Sample E), while Sample A was ground for 3 hr (Sample F) and 1 hr (Sample G). Nanoparticles of GEPs with ranges of 300 nm similar to 1 mu m and 500 nm similar to 3 mu m were produced. The heavy metal content (As, Cd, Co, Cu, Fe, Hg, Mn, Ni, Pb, Se and W) of Samples A-G were all under the maximum residue limit. Sample C contained a higher amount of yellow crystal material and had the highest ginsenoside contents and antioxidant capacity. There were enrichments of ginsenosides (similar to 1.3 fold) and antioxidant capacities (similar to 1.6 fold) in Sample C compared to Sample A. Moreover, after nano-fabrication, the antioxidant capacity was not changed significantly. However, the cellular growth enhancement ability was increased significantly. Samples F and G had the higher cellular growth enhancement ability and improved the cellular growth of L929 cells about 1.3 times as compared to Sample A. In future studies, Sample C will be used for nanofabrication in order to enhance the curative efficiency of ginseng.
ISSN: 1533-4880
DOI: 10.1166/jnn.2009.M18
Appears in Collections:期刊論文

Show full item record

Google ScholarTM




Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.