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|標題:||Implantation of VX2 carcinoma into the liver of rabbits: A comparison of three direct-injection methods||作者:||Lin, W.Y.
|關鍵字:||leakage;liver tumor;VX2 carcinoma cell;y-90 microspheres;hepatic-artery;animal-model;mitomycin-c;iodized;oil;cancer;tumors;therapy||Project:||Journal of Veterinary Medical Science||期刊/報告no：:||Journal of Veterinary Medical Science, Volume 64, Issue 7, Page(s) 649-652.||摘要:||
The efficacy of agarose in preventing VX2 carcinoma cell leakage was evaluoted and the results were compared with two traditional methods. Forty-five rabbits were divided into 3 groups: Group 1, VX2 tumor cells were injected directly into the liver and no special procedure after removal of the needle; Group 2, the puncture site was gently compressed, using an alcoholic cotton gauze, for three minutes; Group 3, 0.2 ml of heated liquid agarose was injected to seal the aperture after injection of VX2 cells. The leakage rates were 80%, 53.3% and 6.6% for group 1, group 2 and group 3, respectively. We consider agarose is a useful material in preventing the leakage in the establishment of VX2 liver tumor models.
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