Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/70854
DC FieldValueLanguage
dc.contributor.authorLee, I.T.en_US
dc.contributor.authorLee, W.J.en_US
dc.contributor.authorTsai, C.M.en_US
dc.contributor.authorSu, I.J.en_US
dc.contributor.authorYen, H.T.en_US
dc.contributor.authorSheu, W.H.H.en_US
dc.date2012zh_TW
dc.date.accessioned2014-06-11T06:00:29Z-
dc.date.available2014-06-11T06:00:29Z-
dc.identifier.issn0271-5317zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/70854-
dc.description.abstractIn this study, we aimed to examine the effects of a plant-extractive compound on lipid profiles in subjects with metabolic syndrome. We hypothesized that extractives from red yeast rice, bitter gourd, chlorella, soy protein, and licorice have synergistic benefits on cholesterol and metabolic syndrome. In this double-blinded study, adult subjects with metabolic syndrome were randomized to receive a plant-extractive compound or a placebo treatment for 12 weeks. Both total cholesterol (5.4 +/- 0.8 to 4.4 +/- 0.6 mtnol/L, P < .001) and low-density lipoprotein cholesterol (3.4 +/- 0.7 to 2.7 +/- 0.5 mmol/L, P < .001) were significantly reduced after treatment with the plant extractives, and the magnitudes of reduction were significantly greater than in the placebo group (-1.0 +/- 0.6 vs 0.0 +/- 0.6 mmol/L, P < .001; -0.7 +/- 0.6 vs 0.0 +/- 0.6 mmol/L, P < .001). The reduction in the fasting triglycerides level was significantly greater in the plant-extractive group than in the placebo group (-0.5 +/- 0.8 vs -0.2 +/- 1.0 mmol/L, P = .039). There was also a significantly greater reduction in the proportion of subjects with hypertensive criteria in the plant-extractive group than in the placebo group (P = .040). In conclusion, the plant extractives from red yeast rice, bitter gourd, chlorella, soy protein, and licorice were effective in reducing total and low-density lipoprotein cholesterol. The plant extractives also showed potential for reducing triglyceride and normalizing blood pressure. (C) 2012 Elsevier Inc. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationNutrition Researchen_US
dc.relation.ispartofseriesNutrition Research, Volume 32, Issue 2, Page(s) 85-92.en_US
dc.relation.urihttp://dx.doi.org/10.1016/j.nutres.2011.12.011en_US
dc.subjectCholesterolen_US
dc.subjectDouble-blinded studyen_US
dc.subjectHumanen_US
dc.subjectMetabolic syndromeen_US
dc.subjectPlaceboen_US
dc.subjectPlant extractivesen_US
dc.subjecthigh-fat dieten_US
dc.subjectprevious myocardial-infarctionen_US
dc.subjectcoronary-heart-diseaseen_US
dc.subjectblood-pressureen_US
dc.subjectmomordica-charantiaen_US
dc.subjecthypercholesterolemic-patientsen_US
dc.subjectglycemic controlen_US
dc.subjectcontrolled-trialen_US
dc.subjectsoybean proteinen_US
dc.subjectglobal burdenen_US
dc.titleCombined extractives of red yeast rice, bitter gourd, chlorella, soy protein, and licorice improve total cholesterol, low-density lipoprotein cholesterol, and triglyceride in subjects with metabolic syndromeen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/j.nutres.2011.12.011zh_TW
item.grantfulltextnone-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.languageiso639-1en_US-
item.fulltextno fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
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