Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/71441
DC FieldValueLanguage
dc.contributor.authorChang, C.Y.en_US
dc.contributor.authorYang, T.K.en_US
dc.date2003zh_TW
dc.date.accessioned2014-06-11T06:01:31Z-
dc.date.available2014-06-11T06:01:31Z-
dc.identifier.issn0957-4166zh_TW
dc.identifier.urihttp://hdl.handle.net/11455/71441-
dc.description.abstractAn enantioselective synthesis of the potent angiotensin converting enzyme (ACE) inhibitor (2S, 3'S)-2-(1-carboxymethyl-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-ylamino)-4-phenylbutyric acid ethyl ester hydrochloride, Benazepril HCl 4, has been achieved through an asymmetric reduction of 4-(2-nitrophenyl)-2,4-dioxobutyric acid ethyl ester 6b employing baker's yeast as the reductive catalyst. (C) 2003 Elsevier Ltd. All rights reserved.en_US
dc.language.isoen_USzh_TW
dc.relationTetrahedron-Asymmetryen_US
dc.relation.ispartofseriesTetrahedron-Asymmetry, Volume 14, Issue 15, Page(s) 2239-2245.en_US
dc.relation.urihttp://dx.doi.org/10.1016/s0957-4166(03)00453-1en_US
dc.subjectangiotensin-converting enzymeen_US
dc.subjectfermenting bakers-yeasten_US
dc.subjectdiastereoselective synthesisen_US
dc.subjectpharmacological propertiesen_US
dc.subjectstereochemicalen_US
dc.subjectcontrolen_US
dc.subjecttherapeutic efficacyen_US
dc.subjectmicrobial reductionen_US
dc.subjectderivativesen_US
dc.subjectestersen_US
dc.subjecthydrogenationen_US
dc.titleAsymmetric synthesis of ACE inhibitor-Benazepril HCl via a bioreductive reactionen_US
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/s0957-4166(03)00453-1zh_TW
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en_US-
item.openairetypeJournal Article-
item.grantfulltextnone-
item.fulltextno fulltext-
item.cerifentitytypePublications-
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