Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/92598
標題: 回溯性創傷性顱腦出血及腦震盪患者血液報告初步分析
Retrospective Analysis of Blood Examination between Traumatic Intracerebral Hemorrhage and Brain Concussion
作者: 鍾偉安
Hui-Ann Chung
關鍵字: 腦震盪;顱腦出血;血液分析;Brain concussion;Traumatic Intracerebral hemorrhage;blood examination
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摘要: 
背景:創傷性顱腦出血是一種腦傷的形式,會導致全世界毀滅性的㦬病率及死亡率。創傷性顱腦出血可以被所謂的腦部電腦斷層診斷。 但是,通常來說在醫療設備缺乏的地方,我們很難辨別病患到底是創傷性顱腦出血亦或是腦震盪。

目的: 本研究主要目的是研究血液分析是否可以當作生物指標來區分創傷性顱腦出血或腦震盪。

方法:我們在本研究採取回溯性、平均分配、隨機取樣各100名的創傷性顱腦出血有接受開刀的病患及100名腦震盪且沒有接受開刀的病患。

結果: 跟腦震盪組比較,創傷性顱腦出血組在白血球、鉀離子、麩胺酸草酸轉胺、丙胺酸胺基轉移酶、C-反應蛋白明顯升高。然而,跟創傷性顱腦出血組比較,腦震盪組在紅血球、血色素、血球容積比明顯升高。

結論: 在血液中3個指標:1. 白血球;2. 麩胺酸草酸轉胺及3. C-反應蛋白也許可以擔任生物指標來診斷創傷性顱腦出血。

Background: Traumatic intracerebral hemorrhage (TICH) is a type of brain injury that results in devastating morbidity and mortality worldwide. TICH can be diagnosed by brain computed tomography scan. However, patients suffering from TICH are difficult to distinguish from those with brain concussion because of insufficient medical data.

Objectives: This study was performed to investigate whether blood tests could be used as biomarkers to distinguish TICH from brain concussion.
Methods: We retrospectively, equally, and randomly compared 100 patients with TICH who received operations and 100 patients with unoperated brain concussion.

Results: The white blood cells (WBCs), potassium, glutamate-oxaloacetate transaminase (GOT), glutamate-pyruvate transaminase, and c-reactive protein (CRP) were elevated in the TICH group compared with the brain concussion group. However, red blood cells, hemoglobin, and hematocrit were elevated in the brain concussion group than those of the TICH group.

Conclusion: Three blood indicators, namely, WBCs, GOT, and CRP, may serve as biomarkers for the diagnosis of TICH.
URI: http://hdl.handle.net/11455/92598
其他識別: U0005-1608201515454000
Rights: 同意授權瀏覽/列印電子全文服務,2015-08-25起公開。
Appears in Collections:生命科學院碩士在職專班

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