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標題: The Characterization of Chicken Infectious Anemia Virus-like Particles Expressed by A Recombinant Fowlpox Virus
作者: Yi-Chia Lo
關鍵字: 雞傳染性貧血病毒;重組禽痘病毒;chicken infectious anemia virus;recombinant fowlpox virus
引用: 呂榮修。1995。雞傳染性貧血。家禽診斷彩色圖譜。中華民國養雞協會。180-189。 鄭雯蓮。2007。雞傳染性貧血病毒VP1及VP2基因分子選殖與表現之研究。碩 士論文。國立屏東科技大學。 Adair B. (2000). Immunopathogenesis of chicken anemia virus infection. Developmental and Comparative Immunology 24(2), 247-255. Afonso C., Tulman E., Lu Z., Zsak L., Kutish G., Rock D. (2000). The genome of fowlpox virus. Journal of Virology 74(8), 3815-3831. Allan G., Phenix K., Todd D., McNulty M. (1994). Some Biological and Physico‐Chemical Properties of Porcine Circovirus. Journal of Veterinary Medicine, Series B 41(1‐10), 17-26. Amer H.M., Elzahed H.M., Elabiare E.A., Badawy A.A., Yousef A.A. (2011). An Optimized Polymerase Chain Reaction Assay to Identify Avian Virus Vaccine Contamination with Chicken Anemia Virus. Journal of Veterinary Diagnostic Investigation 23(1), 34-40. Barbour E., Farran M., Hamadeh S., Bouljihad M., Faroon O., Kreydiyyeh S. (2002). Comparative impact of live chicken infectious anaemia virus vaccine versus natural exposure in meat chicken breeders on immunity to infectivity by CIA and inclusion body hepatitis viruses in their offspring. Veterinary Research Communications 26(5), 397-405. Bougiouklis P., Sofia M., Brellou G., Georgopoulou I., Billinis C., Vlemmas I. (2007). A clinical case of chicken infectious anemia disease and virus DNA detection in naturally infected broilers in Greece. Avian Diseases 51(2), 639-642. Boyle D., Heine H. (1993). Recombinant fowlpox virus vaccines for poultry. Immunology and Cell Biology 71, 391-391. Boyle D.B., Coupar B.E. (1986). Identification and cloning of the fowlpox virus thymidine kinase gene using vaccinia virus. Journal of General Virology 67(8), 1591-1600. Brentano L., Lazzarin S., Bassi S.S., Klein T.A., Schat K.A. (2005). Detection of chicken anemia virus in the gonads and in the progeny of broiler breeder hens with high neutralizing antibody titers. Veterinary Microbiology 105(1), 65-72. Brentano L., Mores N., Wentz I., Chandratilleke D., Schat K.A. (1991). Isolation and identification of chicken infectious anemia virus in Brazil. Avian Diseases, 793-800. Brown K., Browning G., Scott P., Crabb B. (2000). Full‐length infectious clone of a pathogenic Australian isolate of chicken anaemia virus. Australian Veterinary Journal 78(9), 637-640. Bublot M., Manvell R.J., Shell W., Brown I.H. (2010). High Level of Protection Induced by Two Fowlpox Vector Vaccines Against a Highly Pathogenic Avian Influenza H5N1 Challenge in Specific-Pathogen-Free Chickens. Avian Diseases 54(s1), 257-261. Butter C., Sturman T.D., Baaten B.J., Davison T.F. (2003). Protection from infectious bursal disease virus (IBDV)-induced immunosuppression by immunization with a fowlpox recombinant containing IBDV-VP2. Avian Pathology 32(6), 597-604. Calnek B.W., Lucio-Martinez B., Cardona C., Harris R.W., Schat K.A., Buscaglia C. (2000). Comparative susceptibility of Marek's disease cell lines to chicken infectious anemia virus. Avian Diseases, 114-124. Calnek B.W., Schat K.A., Peckham M.C., Fabricant J. (1983). Field trials with a bivalent vaccine (HVT and SB-1) against Marek's disease. Avian Diseases 27(3), 844-849. Cardona C.J., Oswald W.B., Schat K. (2000). Distribution of chicken anaemia virus in the reproductive tissues of specific-pathogen-free chickens. Journal of General Virology 81(8), 2067-2075. Chakrabarti S., Sisler J., Moss B. (1997a). Compact, synthetic, vaccinia virus early/late promoter for protein expression. Biotechniques 23(6), 1094-1097. Chakrabarti S., Sisler J.R., Moss B. (1997b). Compact, synthetic, vaccinia virus early/late promoter for protein expression. Biotechniques 23(6), 1094-1097. Chen H.Y., Cui P., Cui B.A., Li H.P., Jiao X.Q., Zheng L.L., Cheng G., Chao A.J. (2011). Immune responses of chickens inoculated with a recombinant fowlpox vaccine coexpressing glycoprotein B of infectious laryngotracheitis virus and chicken IL-18. FEMS Immunology and Medical Microbiology 63(2), 289-295. Chen H.Y., Yang M.F., Cui B.A., Cui P., Sheng M., Chen G., Wang S.J., Geng J.W. (2010). Construction and immunogenicity of a recombinant fowlpox vaccine coexpressing S1 glycoprotein of infectious bronchitis virus and chicken IL-18. Vaccine 28(51), 8112-8119. Chettle N., Eddy R., Wyeth P., Lister S. (1989). An outbreak of disease due to chicken anaemia agent in broiler chickens in England. The Veterinary Record 124(9), 211-215. Chowdhury S., Omar A., Aini I., Hair-Bejo M., Jamaluddin A., Md-Zain B., Kono Y. (2003a). Pathogenicity, sequence and phylogenetic analysis of Malaysian Chicken anaemia virus obtained after low and high passages in MSB-1 cells. Archives of Virology 148(12), 2437-2448. Chowdhury S.M., Omar A.R., Aini I., Hair-Bejo M., Jamaluddin A.A., Md-Zain B.M., Kono Y. (2003b). Pathogenicity, sequence and phylogenetic analysis of Malaysian Chicken anaemia virus obtained after low and high passages in MSB-1 cells. Archives of Virology 148(12), 2437-2448. Claessens J., Schrier C.C., Mockett A., Jagt E., Sondermeijer P. (1991). Molecular cloning and sequence analysis of the genome of chicken anaemia agent. Journal of General Virology 72, 2003-2006. Cloud S., Lillehoj H., Rosenberger J. (1992). Immune dysfunction following infection with chicken anemia agent and infectious bursal disease virus. I. Kinetic alterations of avian lymphocyte subpopulations. Veterinary Immunology and Immunopathology 34(3), 337-352. Craig M.I., Rimondi A., Delamer M., Sansalone P., König G., Vagnozzi A., Pereda A. (2009). Molecular characterization of chicken infectious anemia virus circulating in Argentina during 2007. Avian Diseases 53(3), 331-335. Davidson I., Artzi N., Shkoda I., Lublin A., Loeb E., Schat K.A. (2008). The contribution of feathers in the spread of chicken anemia virus. Virus Research 132(1-2), 152-159. De Boer G., van Roozelaar D., Moormann R., Jeurissen S., van Den Wijngaard J., Hilbink F., Koch G. (1994). Interaction between chicken anaemia virus and live Newcastle disease vaccine. Avian Pathology 23(2), 263-275. Du S., Liu C., Zhu Y., Wang Y., Ren D., Wang M., Tan P., Li X., Tian M., Zhang Y. (2015). Construction and characterization of novel fowlpox virus shuttle vectors. Virus Research 197, 59-66. Ducatez M., Owoade A., Abiola J., Muller C. (2006). Molecular epidemiology of chicken anemia virus in Nigeria. Archives of Virology 151(1), 97-111. Eleazer T.H., Harrell J.S., Blalock H.G. (1983). Transmission studies involving a wet fowl pox isolate. Avian Diseases, 542-544. Engström B. (1998a). Prevalence of antibody to chicken anaemia virus (CAV) in Swedish chicken breeding flocks correlated to outbreaks of blue wing disease (BWD) in their progeny. Acta Veterinaria Scandinavica 40(2), 97-107. Engström B. (1998b). Prevalence of antibody to chicken anaemia virus (CAV) in Swedish chicken breeding flocks correlated to outbreaks of blue wing disease (BWD) in their progeny. Acta Veterinaria Scandinavica 40(2), 97-107. Engström B., Fossum O., Luthman M. (1988). Blue wing disease of chickens: experimental infection with a Swedish isolate of chicken anaemia agent and an avian reovirus. Avian Pathology 17(1), 33-50. Engström B., Luthman M. (1984). Blue wing disease of chickens: signs, pathology and natural transmission. Avian Pathology 13(1), 1-12. Firth G., Imai K. (1990). Isolation of chicken anaemia agent from Australian poultry. Australian Veterinary Journal 67(8), 301-302. Gelderblom H., Kling S., Lurz R., Tischer I., Bülow V.v. (1989). Morphological characterization of chicken anaemia agent (CAA). Archives of Virology 109(1-2), 115-120. Gharaibeh S., Mahmoud K. (2013). Decay of maternal antibodies in broiler chickens. Poultry Science 92(9), 2333-2336. Goodwin M., Brown J., Davis J., Girshick T., Miller S., Nordgren R., Rodenberg J. (1992a). Comparisons of packed cell volumes (PCVs) from so-called chicken anemia agent (CAA; a virus)-free broilers to PCVs from CAA-free specific-pathogen-free leghorns. Avian Diseases, 1063-1066. Goodwin M.A., Davis J.F., Brown J. (1992b). Packed cell volume reference intervals to aid in the diagnosis of anemia and polycythemia in young broiler chickens. Avian Diseases, 440-443. Goryo M., Shibata Y., Suwa T., Umemura T., Itakura C. (1987a). Outbreak of anemia associated with chicken anemia agent in young chicks. Nihon juigaku zasshi. The Japanese journal of veterinary science 49(5), 867. Goryo M., Sugimura H., Matsumoto S., Umemura T., Itakura C. (1985). Isolation of an agent inducing chicken anaemia. Avian Pathology 14(4), 483-496. Goryo M., Suwa T., Matsumoto S., Umemura T., Itakura C. (1987b). Serial propagation and purification of chicken Anaemia agent in mdcc‐MSB1 cell line. Avian Pathology 16(1), 149-163. Goryo M., Suwa T., Umemura T., Itakura C., Yamashiro S. (1989a). Histopathology of chicks inoculated with chicken anaemia agent (MSB1‐TK5803 strain). Avian Pathology 18(1), 73-89. Goryo M., Suwa T., Umemura T., Itakura C., Yamashiro S. (1989b). Ultrastructure of bone marrow in chicks ioculated with chicken aaemia agent (MSB1‐TK5803 strain). Avian Pathology 18(2), 329-343. Guo K.K., Zhang W.M., Zhang Y.M., Ning P.B., Wang J.Y., Zhang M.T. (2011). Construction of a recombinant Fowlpox virus expressing the E0/E2 proteins of classical swine fever virus and its evaluation in experimental animals. Asian Journal of Animal and Veterinary Advances 6(7), 654-666. Hara H., Monsonego A., Yuasa K., Adachi K., Xiao X., Takeda S., Takahashi K., Weiner H.L., Tabira T. (2004). Development of a safe oral Abeta vaccine using recombinant adeno-associated virus vector for Alzheimer's disease. Journal of Alzheimer's Disease 6(5), 483-488. Haridy M., Sasaki J., Okada K., Goryo M. (2012). Persistence of inclusions and antigens of chicken anemia virus in Marek's disease lymphoma. Research in Veterinary Science 93(3), 1353-1360. Hasmah M., Omar A., Wan K., Hair-Bejo M., Aini I. (2003). Genetic diversity of chicken anemia virus following cell culture passaging in MSB-1 cells. Acta Virologica 48(2), 85-89. Hierholzer J., Killington R. (1996). Virus isolation and quantitation. Virology methods manual, 25-46. Hoop R. (1993). Transmission of chicken anaemia virus with semen. Veterinary Record 133(22), 551-552. Hoop R., Reece R. (1991). The use of immunofluorescence and immunoperoxidase staining in studying the pathogenesis of chicken anaemia agent in experimentally infected chickens. Avian Pathology 20(2), 349-355. Hoop R.K. (1992). Persistence and vertical transmission of chicken anaemia agent in experimentally infected laying hens. Avian Pathology 21(3), 493-501. Imler J.L. (1995). Adenovirus vectors as recombinant viral vaccines. Vaccine 13(13), 1143-1151. Islam M., Johne R., Raue R., Todd D., Müller H. (2002). Sequence Analysis of the Full‐Length Cloned DNA of a Chicken Anaemia Virus (CAV) Strain from Bangladesh: Evidence for Genetic Grouping of CAV Strains Based on the Deduced VP1 Amino Acid Sequences. Journal of Veterinary Medicine, Series B 49(7), 332-337. Jeurissen S., Pol J., De Boer G. (1988). Transient depletion of cortical thymocytes induced by chicken anaemia agent. Thymus 14(1-3), 115-123. Jeurissen S., Wagenaar F., Pol J., van der Eb A., Noteborn M. (1992). Chicken anemia virus causes apoptosis of thymocytes after in vivo infection and of cell lines after in vitro infection. Journal of Virology 66(12), 7383-7388. Kaffashi A., Noormohammadi A.H., Allott M.L., Browning G.F. (2006). Viral load in 1-day-old and 6-week-old chickens infected with chicken anaemia virus by the intraocular route. Avian Pathology 35(6), 471-474. Kapczynski D.R., Esaki M., Dorsey K.M., Jiang H., Jackwood M., Moraes M., Gardin Y. (2015). Vaccine protection of chickens against antigenically diverse H5 highly pathogenic avian influenza isolates with a live HVT vector vaccine expressing the influenza hemagglutinin gene derived from a clade 2.2 avian influenza virus. Vaccine 33(9), 1197-1205. Kim H.R., Kwon Y.K., Bae Y.C., Oem J.K., Lee O.S. (2010). Molecular characterization of chicken infectious anemia viruses detected from breeder and broiler chickens in South Korea. Poultry Science 89(11), 2426-2431. Koch G. (2000). Studies on the pathogenesis of chicken infectious anemia virus infection in six-week-old SPF chickens. Acta Veterinaria Hungarica 48(4), 455-467. Koch G., van Roozelaar D.J., Verschueren C.A., van der Eb A.J., Noteborn M.H. (1995). Immunogenic and protective properties of chicken anaemia virus proteins expressed by baculovirus. Vaccine 13(8), 763-770. Krapež U., Barlič-Maganja D., Toplak I., Hostnik P., Rojs O.Z. (2006). Biological and Molecular Characterization of Chicken Anemia Virus Isolates from Slovenia. Avian Diseases 50(1), 69-76. Kye S.J., Kim J.Y., Seul H.J., Kim S., Kim S.E., Lee H.S., Sorn S., Choi K.S. (2013). Phylogenetic analysis and genetic characterization of chicken anemia virus isolates from Cambodia. Poultry Science 92(10), 2681-2686. Lee M.S., Lai G.H., Fu J.H., Huang C.H., Chen H.J., Tzen J.T., Lien Y.Y., Lin M.K. (2013). Expression and characterization of highly antigenic domains of chicken anemia virus viral VP2 and VP3 subunit proteins in a recombinant E. coli for sero-diagnostic applications. BMC veterinary research 9(1), 161-170. Lee M.S., Lien Y.Y., Feng S.H., Huang R.L., Tsai M.C., Chang W.T., Chen H.J. (2009). Production of chicken anemia virus (CAV) VP1 and VP2 protein expressed by recombinant Escherichia coli. Process Biochemistry 44(4), 390-395. Lee M.S., Chou Y.M., Lien Y.Y., Lin M.K., Chang W.T., Lee H.Z., Lee M.S., Lai G.H., Chen H.J., Huang C.H., Lin W.H. (2011a). Production and diagnostic application of a purified, E. coli-expressed, serological-specific chicken anaemia virus antigen VP3. Transboundary and Emerging Diseases 58(3), 232-239. Lee M.S., Hseu Y.C., Lai G.H., Chang W.T., Chen H.J., Huang C.H., Lee M.S., Wang M.Y., Kao J.Y., You B.J., Lin W., Lien Y.Y., Lin M.K. (2011b). High yield expression in a recombinant E. coli of a codon optimized chicken anemia virus capsid protein VP1 useful for vaccine development. Microbial Cell Factories 10(1), 56-67. Lucio B., Schat K., Shivaprasad H. (1990). Identification of the chicken anemia agent, reproduction of the disease, and serological survey in the United States. Avian Diseases, 146-153. Markowski-Grimsrud C.J., Miller M.M., Schat K.A. (2002). Development of strain-specific real-time PCR and RT-PCR assays for quantitation of chicken anemia virus. Journal of Virological Methods 101(1), 135-147. Markowski‐Grimsrud C.J., Schat K.A. (2003). Infection with chicken anaemia virus impairs the generation of pathogen‐specific cytotoxic T lymphocytes. Immunology 109(2), 283-294. McConnell C., Adair B., McNulty M. (1993). Effects of chicken anemia virus on cell-mediated immune function in chickens exposed to the virus by a natural route. Avian Diseases, 366-374. McKenna G.F., Todd D., Borghmans B.J., Welsh M.D., Adair B.M. (2003). Immunopathologic Investigations with an Attenuated Chicken Anemia Virus in Day-Old Chickens. Avian Diseases 47(4), 1339-1345. McNulty M. (1991a). Chicken anaemia agent: a review. Avian Pathology 20(2), 187-203. McNulty M., Curran W., Todd D., Mackie D. (1990a). Chicken anemia agent: an electron microscopic study. Avian Diseases, 736-743. McNulty M., Mackie D., Pollock D., McNair J., Todd D., Mawhinney K., Connor T., McNeilly F. (1990b). Production and preliminary characterization of monoclonal antibodies to chicken anemia agent. Avian Diseases, 352-358. McNulty M., McIlroy S., Bruce D., Todd D. (1991). Economic effects of subclinical chicken anemia agent infection in broiler chickens. Avian Diseases, 263-268. McNulty M.S. (1991b). Chicken anaemia agent: a review. Avian Pathology 20(2), 187-203. McNulty M.S., Connor T.J., McNeilly F. (1989). A survey of specific pathogen-free chicken flocks for antibodies to chicken anaemia agent, avian nephritis virus and group a rotavirus. Avian Pathology 18(2), 215-220. Mehendale S., Sahay S., Thakar M., Sahasrabuddhe S., Kakade M., Shete A., Shrotri A., Spentzou A., Tarragona T., Stevens G., Kochhar S., Excler J.L., Fast P., Paranjape R. (2010). Safety & immunogenicity of tgAAC09, a recombinant adeno-associated virus type 2 HIV-1 subtype C vaccine in India. Indian Journal of Medical Research 132, 168-175. Mete A., Borst G.H., Dorrestein G.M. (2001). Atypical poxvirus lesions in two Galapagos doves (Nesopelia g. galapagoensis). Avian Pathology 30(2), 159-162. Miller M.M., Ealey K.A., Oswald W.B., Schat K.A. (2003). Detection of Chicken Anemia Virus DNA in Embryonal Tissues and Eggshell Membranes. Avian Diseases 47(3), 662-671. Miller M.M., Schat K. (2004). Chicken infectious anemia virus: an example of the ultimate host-parasite relationship. Avian Diseases 48(4), 734-745. Mockett A., Southee D., Tomley F., Deuter A. (1987). Fowlpox virus: Its structural proteins and immunogens and the detection of viral‐specific antibodies by Elisa. Avian Pathology 16(3), 493-504. Moeini H., Omar A.R., Rahim R.A., Yusoff K. (2011a). Development of a DNA vaccine against chicken anemia virus by using a bicistronic vector expressing VP1 and VP2 proteins of CAV. Comparative Immunology, Microbiology & Infectious Diseases 34(3), 227-236. Moeini H., Omar A.R., Rahim R.A., Yusoff K. (2011b). Improving the potency of DNA vaccine against chicken anemia virus (CAV) by fusing VP1 protein of CAV to Marek's Disease Virus (MDV) type-1 VP22 protein. Journal of Virology 8, 119. Moeini H., Rahim R.A., Omar A.R., Shafee N., Yusoff K. (2011c). Lactobacillus acidophilus as a live vehicle for oral immunization against chicken anemia virus. Applied Microbiology and Biotechnology 90(1), 77-88. Moss B. (1996). Genetically engineered poxviruses for recombinant gene expression, vaccination, and safety. Proceedings of the National Academy of Sciences 93(21), 11341-11348. Natesan S., Kataria J., Dhama K., Rahul S., Baradhwaj N. (2006a). Biological and molecular characterization of chicken anaemia virus isolates of Indian origin. Virus Research 118(1), 78-86. Natesan S., Kataria J.M., Dhama K., Bhardwaj N., Sylvester A. (2006b). Anti-neoplastic effect of chicken anemia virus VP3 protein (apoptin) in Rous sarcoma virus-induced tumours in chicken. Journal of General Virology 87(Pt 10), 2933-2940. Natesan S., Kataria J.M., Dhama K., Rahul S., Bhardwaj N. (2006c). Biological and molecular characterization of chicken anaemia virus isolates of Indian origin. Virus Resarch 118(1-2), 78-86. Nayabian H., Mardani K. (2013). Molecular characterization of the chicken anaemia viruses isolated from broiler farms of west Azerbaijan, Iran. Avian Pathology 42(2), 108-113. Nazerian K., Lee L., Yanagida N., Ogawa R. (1992). Protection against Marek's disease by a fowlpox virus recombinant expressing the glycoprotein B of Marek's disease virus. Journal of Virology 66(3), 1409-1413. Nazerian K., Witter R., Lee L., Yanagida N. (1996). Protection and synergism by recombinant fowl pox vaccines expressing genes from Marek's disease virus. Avian Diseases, 368-376. Nogueira E., Brentano L., Ferreira A. (2005). A VP3/VP1 gene polymerase chain reaction assay for detection of chicken anemia virus in broiler samples. Arquivo Brasileiro de Medicina Veterinária e Zootecnia 57, 131-140. Noteborn M., De Boer G., van Roozelaar D., Karreman C., Kranenburg O., Vos J., Jeurissen S., Hoeben R., Zantema A., Koch G. (1991). Characterization of cloned chicken anemia virus DNA that contains all elements for the infectious replication cycle. Journal of Virology 65(6), 3131-3139. Noteborn M., Todd D., Verschueren C., De Gauw H., Curran W., Veldkamp S., Douglas A.J., McNulty M., Koch G. (1994). A single chicken anemia virus protein induces apoptosis. Journal of Virology 68(1), 346-351. Noteborn M., Verschueren C., Koch G., van der Eb A.J. (1998). Simultaneous expression of recombinant baculovirus-encoded chicken anaemia virus (CAV) proteins VP1 and VP2 is required for formation of the CAV-specific neutralizing epitope. Journal of General Virology 79(12), 3073-3077. Noteborn M., Verschueren C., van Roozelaar D., Veldkamp S., van Der Eb A., De Boer G. (1992). Detection of chicken anaemia virus by DNA hybridization and polymerase chain reaction. Avian Pathology 21(1), 107-118. Otaki Y., Nunoya T., Tajima M., Saito K., Nomura Y. (1989). Enhanced pathogenicity of chicken anemia agent by infectious bursal disease virus relative to the occurrence of Marek's disease vaccination breaks. Nihon juigaku zasshi. The Japanese journal of veterinary science 51(4), 849-852. Pallister J., Fahey K.J., Sheppard M. (1994). Cloning and sequencing of the chicken anaemia virus (CAV) ORF-3 gene, and the development of an ELISA for the detection of serum antibody to CAV. Veterinary Microbiology 39(1), 167-178. Paoletti E. (1996). Applications of pox virus vectors to vaccination: an update. Proceedings of the National Academy of Sciences 93(21), 11349-11353. Peters M.A., Jackson D.C., Crabb B.S., Browning G.F. (2005). Mutation of chicken anemia virus VP2 differentially affects serine/threonine and tyrosine protein phosphatase activities. Journal of General Virology 86(Pt 3), 623-630. Pope C.R. (1991). Chicken anemia agent. Veterinary Immunology and Immunopathology 30(1), 51-65. Pringle C. (1999). Virus taxonomy at the XIth international congress of virology, Sydney, Australia, 1999. Archives of Virology 144(10), 2065-2070. Qin X., Lu H., Jin K., Zheng M., Tian M., Li C., Niu J., Jin N., Shan H. (2014). Immune responses of pigs inoculated with a recombinant fowlpox virus coexpressing ORF2/ORF1 of PCV2 and P1 2A of FMDV. African Journal of Biotechnology 11(27), 7135-7144. Rautenschlein S., Yeh H.-Y., Njenga M., Sharma J. (2002). Role of intrabursal T cells in infectious bursal disease virus (IBDV) infection: T cells promote viral clearance but delay follicular recovery. Archives of Virology 147(2), 285-304. Rauw F., Gardin Y., Palya V., Anbari S., Lemaire S., Boschmans M., van den Berg T., Lambrecht B. (2010). Improved vaccination against Newcastle disease by an in ovo recombinant HVT-ND combined with an adjuvanted live vaccine at day-old. Vaccine 28(3), 823-833. Renshaw R.W., Soiné C., Weinkle T., O'Connell P.H., Ohashi K., Watson S., Lucio B., Harrington S., Schat K.A. (1996). A hypervariable region in VP1 of chicken infectious anemia virus mediates rate of spread and cell tropism in tissue culture. Journal of Virology 70(12), 8872-8878. Rosenberger J.K., Cloud S.S. (1989). The effects of age, route of exposure, and coinfection with infectious bursal disease virus on the pathogenicity and transmissibility of chicken anemia agent (CAA). Avian Diseases, 753-759. Schat K.A., da Silva Martins N.R., O'Connell P.H., Piepenbrink M.S. (2011). Immune Complex Vaccines for Chicken Infectious Anemia Virus. Avian Diseases 55(1), 90-96. Schat K.A., van Santen V.L. (2007). Chicken infectious anemia. In Y.M. Saif, A.M. Fadly, J.R. Glisson, L.R. McDougald, L.K. Nolan & D.E. Swayne (Eds.), Diseases of Poultry,12 th edn (pp.211-249). Ames: Iowa State Press. Scott A., Connor T., Creelan J., McNulty M., Todd D. (1999). Antigenicity and pathogenicity characteristics of molecularly cloned chicken anaemia virus isolates obtained after multiple cell culture passages. Archives of Virology 144(10), 1961-1975. Scott A., McNulty M., Todd D. (2001). Characterisation of a chicken anaemia virus variant population that resists neutralisation with a group-specific monoclonal antibody. Archives of Virology 146(4), 713-728. Sheela R.R., Babu U., Mu J., Elankumaran S., Bautista D.A., Raybourne R.B., Heckert R.A., Song W. (2003). Immune responses against Salmonella enterica serovar enteritidis infection in virally immunosuppressed chickens. Clinical and Diagnostic Laboratory Immunology 10(4), 670-679. Shen G., Jin N., Ma M., Jin K., Zheng M., Zhuang T., Lu H., Zhu G., Jin H., Jin M., Huo X., Qin X., Yin R., Li C., et al. (2007). Immune responses of pigs inoculated with a recombinant fowlpox virus coexpressing GP5/GP3 of porcine reproductive and respiratory syndrome virus and swine IL-18. Vaccine 25(21), 4193-4202. Shi X.M., Zhao Y., Gao H.B., Jing Z., Wang M., Cui H.Y., Tong G.Z., Wang Y.F. (2011). Evaluation of recombinant fowlpox virus expressing infectious bronchitis virus S1 gene and chicken interferon-gamma gene for immune protection against heterologous strains. Vaccine 29(8), 1576-1582. Simionatto S., Lima-Rosa C.A., Binneck E., Ravazzolo A.P., Canal C.W. (2006). Characterization and phylogenetic analysis of Brazilian chicken anaemia virus. Virus Genes 33(1), 5-10. Singh P., Kim T.-J., Tripathy D. (2000). Re-emerging fowlpox: evaluation of isolates from vaccinated flocks. Avian Pathology 29(5), 449-455. Skinner M.A., Laidlaw S.M., Eldaghayes I., Kaiser P., Cottingham M.G. (2005). Fowlpox virus as a recombinant vaccine vector for use in mammals and poultry. Expert Review of Vaccines 4(1), 63-76. Smyth J., Moffett D., McNulty M., Todd D., Mackie D. (1993). A sequential histopathologic and immunocytochemical study of chicken anemia virus infection at one day of age. Avian Diseases, 324-338. Smyth J.A., Moffett D.A., Connor T.J., McNulty M.S. (2006). Chicken anaemia virus inoculated by the oral route causes lymphocyte depletion in the thymus in 3-week-old and 6-week-old chickens. Avian Pathology 35(3), 254-259. Soine C., Watson S., Rybicki E., Lucio B., Nordgren R., Parrish C., Schat K.A. (1993). Determination of the detection limit of the polymerase chain reaction for chicken infectious anemia virus. Avian Diseases, 467-476. Sommer F., Cardona C. (2003). Chicken Anemia Virus in Broilers: Dynamics of the Infection in Two Commercial Broiler Flocks. Avian Diseases 47(4), 1466-1473. Steenhuisen W., Jagt H., Schrier C. (1994). The use of live attenuated CAV vaccine in breeder flocks in the Netherlands. International symposium on infectious bursal disease and chicken infectious anaemia, Rauischholzhausen, Germany, 482-497. Su B.S., Chiu H.H., Lin C.C., Shien J.H., Yin H.S., Lee L.H. (2011a). Adjuvant activity of chicken interleukin-12 co-administered with infectious bursal disease virus recombinant VP2 antigen in chickens. Veterinary Immunology and Immunopathology 139(2-4), 167-175. Su B.S., Shen P.C., Hung L.H., Huang J.P., Yin H.S., Lee L.H. (2011b). Potentiation of cell-mediated immune responses against recombinant HN protein of Newcastle disease virus by recombinant chicken IL-18. Veterinary Immunology and Immunopathology 141(3), 283-292. Su B.S., Yin H.S., Shien J.H., Chiu H.H., Lee L.H. (2010). Production of biologically active chicken interleukin (IL)-12 and IL-18 synthesized by the recombinant fowlpox virus. Process Biochemistry 45(7), 1057-1064. Tan J., Tannock G.A. (2005a). Role of viral load in the pathogenesis of chicken anemia virus. Journal of General Virology 86(Pt 5), 1327-1333. Tan J., Tannock G.A. (2005b). Role of viral load in the pathogenesis of chicken anemia virus. Journal of General Virology 86(5), 1327-1333. Taniguchi T., Yuasa N., Maeda M., Horiuchi T. (1982). Chronological observations on hemato-pathological changes in chicks inoculated with chicken anemia agent. National Institute of Animal Health Quarterly 23(1), 1-12. Tannock G., Tan J., Mawhinney K., Todd D., O'ROURKE D., Bagust T. (2003). A modified blocking ELISA for the detection of antibody to chicken anaemia virus using an Australian strain. Australian Veterinary Journal 81(7), 428-430. Todd D. (2000). Circoviruses: immunosuppressive threats to avian species: a review. Avian Pathology 29(5), 373-394. Todd D., Connor T.J., Calvert V.M., Creelan J.L., Meehan B.M., McNulty M.S. (1995). Molecular cloning of an attenuated chicken anaemia virus isolate following repeated cell culture passage. Avian Pathology 24(1), 171-187. Todd D., Creelan J.L., Connor T.J., Ball N.W., Scott A.N., Meehan B.M., McKenna G.F., McNulty M.S. (2003). Investigation of the unstable attenuation exhibited by a chicken anaemia virus isolate. Avian Pathology 32(4), 375-382. Todd D., Mackie D., Mawhinney K., Connor T., McNeilly F., McNulty M. (1990). Development of an enzyme-linked immunosorbent assay to detect serum antibody to chicken anemia agent. Avian Diseases, 359-363. Toro H., Gonzalez C., Cerda L., Hess M., Reyes E., Geisse C. (2000). Chicken anemia virus and fowl adenoviruses: association to induce the inclusion body hepatitis/hydropericardium syndrome. Avian Diseases, 51-58. Toro H., Ramirez A.M., Larenas J. (1997). Pathogenicity of chicken anaemia virus (isolate 10343) for young and older chickens. Avian Pathology 26(3), 485-499. Toro H., van Santen V., Li L., Lockaby S., van Santen E., Hoerr F. (2006). Epidemiological and experimental evidence for immunodeficiency affecting avian infectious bronchitis. Avian Pathology 35(6), 455-464. Toro H., van Santen V.L., Hoerr F.J., Breedlove C. (2009). Effects of Chicken Anemia Virus and Infectious Bursal Disease Virus in Commercial Chickens. Avian Diseases 53(1), 94-102. Trinh D.Q., Ogawa H., Bui V.N., Baatartsogt T., Kizito M.K., Yamaguchi S., Imai K. (2015). Characterization of monoclonal antibodies to chicken anemia virus and epitope mapping on its viral protein, VP1. Journal of General Virology. Urlings H., De Boer G., van Roozelaar D., Koch G. (1993). Inactivation of chicken anaemia virus in chickens by heating and fermentation. Veterinary Quarterly 15(3), 85-88. van Santen V.L., Joiner K.S., Murray C., Petrenko N., Hoerr F.J., Toro H. (2004). Pathogenesis of Chicken Anemia Virus: Comparison of the Oral and the Intramuscular Routes of Infection. Avian Diseases 48(3), 494-504. van Santen V.L., Toro H., Hoerr F.J. (2007). Biological characteristics of chicken anemia virus regenerated from clinical specimen by PCR. Avian Diseases 51(1), 66-77. Vaziry A., Silim A., Bleau C., Frenette D., Lamontagne L. (2011). Chicken infectious anaemia vaccinal strain persists in the spleen and thymus of young chicks and induces thymic lymphoid cell disorders. Avian Pathology 40(4), 377-385. Vaziry A., Silim A., Bleau C., Frenette D., Lamontagne L. (2013). Dual infections with low virulent chicken infectious anaemia virus (lvCIAV) and intermediate infectious bursal disease virus (iIBDV) in young chicks increase lvCIAV in thymus and bursa while decreasing lymphocyte disorders induced by iIBDV. Avian Pathology 42(2), 88-99. Vielitz E., Landgraf H. (1988). Anaemia‐dermatitis of broilers: Field observations on its occurrence, transmission and prevention. Avian Pathology 17(1), 113-120. von Bülow V., Fuchs B., Vielitz E., Landgraf H. (1983). Frühsterblichkeitssyndrom bei Küken nach Doppelinfektion mit dem Virus der Marekschen Krankheit (MDV) und einem Anämie‐Erreger (CAA). Zentralblatt für Veterinärmedizin Reihe B 30(1‐10), 742-750. von Bülow V., Rudolph R., Fuchs B. (1986). Erhöhte Pathogenität des Erregers der aviären infektiösen Anämie bei Hühnerküken (CAA) bei simultaner Infektion mit Virus der Marekschen Krankheit (MDV), Bursitisvirus (IBDV) oder Reticuloendotheliosevirus (REV). Journal of Veterinary Medicine, Series B 33(1‐10), 93-116. von Bülow V. (1991). Avian infectious anemia and related syndromes caused by chicken anemia virus. Critical reviews in poultry biology 3(1), 1-17. Wang X., Gao H., Gao Y., Fu C., Wang Z., Lu G., Cheng Y., Wang X. (2007). Mapping of epitopes of VP2 protein of chicken anemia virus using monoclonal antibodies. Journal of Virological Methods 143(2), 194-199. Yamaguchi S., Imada T., Kaji N., Mase M., Tsukamoto K., Tanimura N., Yuasa N. (2001). Identification of a genetic determinant of pathogenicity in chicken anaemia virus. Journal of General Virology 82(5), 1233-1238. Yamaguchi S., Kaji N., Munang'andu H.M., Kojima C., Mase M., Tsukamoto K. (2000). Quantification of chicken anaemia virus by competitive polymerase chain reaction. Avian Pathology 29(4), 305-310. Yang J., Wang J., Zuo Y., Zhan H. (2012). Molecularly modified VP3 (30-121) induces apoptosis in human bladder cancer (EJ) cells but not in normal (3T3) cells. Cell Biology International 36(11), 1037-1042. Yuasa, N. (1983). Propagation and infectivity titration of the Gifu-1 strain of chicken anemia agent in a cell line (MDCC-MSB1) derived from Marek's disease lymphoma. National Institute of Animal Health Quarterly (Japan) 23, 13–20. Yuasa N. (1992). Effect of chemicals on the infectivity of chicken anaemia virus. Avian Pathology 21(2), 315-319. Yuasa N., Imai K. (1986). Pathogenicity and antigenicity of eleven isolates of chicken anaemia agent (CAA). Avian Pathology 15(4), 639-645. Yuasa N., Imai K., Tezuka H. (1985). Survey of antibody against chicken anaemia agent (CAA) by an indirect immunofluorescent antibody technique in breeder flocks in Japan. Avian Pathology 14(4), 521-530. Yuasa N., Noguchi T., Furuta K., Yoshida I. (1980a). Maternal antibody and its effect on the susceptibility of chicks to chicken anemia agent. Avian Diseases, 197-201. Yuasa N., Taniguchi T., Imada T., Hihara H. (1982a). Distribution of chicken anemia agent (CAA) and detection of neutralizing antibody in chicks experimentally inoculated with CAA. National Institute of Animal Health Quarterly 23(3), 78-81. Yuasa N., Taniguchi T., Noguchi T., Yoshida I. (1980b). Effect of infectious bursal disease virus infection on incidence of anemia by chicken anemia agent. Avian Diseases, 202-209. Yuasa N., Taniguchi T., Yoshida I. (1979). Isolation and some characteristics of an agent inducing anemia in chicks. Avian Diseases 23, 366-385. Yuasa N., Yoshida I. (1982b). Experimental egg transmission of chicken anemia agent. National Institute of Animal Health Quarterly 23(3), 99-100. Zanotto C., Pozzi E., Pacchioni S., Bissa M., De Giuli Morghen C., Radaelli A. (2011). Construction and characterisation of a recombinant fowlpox virus that expresses the human papilloma virus L1 protein. Journal of Translational Medicine 9, 190-200. Zhang X., Liu Y., Wu B., Sun B., Chen F., Ji J., Ma J., Xie Q. (2013a). Phylogenetic and molecular characterization of chicken anemia virus in southern China from 2011 to 2012. Scientific Reports 3, 3519. Zhang X., Xie Q., Ji J., Chang S., Liu J., Chen F., Ma J., Bee Y. (2012). Complete genome sequence analysis of a recent chicken anemia virus isolate and comparison with a chicken anemia virus isolate from human fecal samples in China. Journal of Virology 86(19), 10896-10897. Zhang Z., Wang L., Fu C., Li X., Cui Z., Zhang J., Xue S., Sun N., Xu F. (2013b). Combination of targeting gene-viro therapy with recombinant Fowl-pox viruses with HN and VP3 genes on mouse osteosarcoma. European Review for Medical and Pharmacological Sciences 17(6), 767-776. Zhou W., Shen B., Yang B., Han S., Wei L., Xiao B., Zhou J. (1997). Isolation and identification of chicken infectious anemia virus in China. Avian Diseases, 361-364.
雞傳染性貧血 (chicken infectious anemia; CIA)主要由雞傳染性貧血病毒(chicken infectious anemia virus; CIAV)造成,此病毒分布全球影響所有國家且尤其對於肉雞產業及提供無特定病原蛋之生產者造成經濟威脅,雖然目前市面上有活毒疫苗用於免疫但推薦施打日齡皆超過6週齡,對於幼齡雞隻無法提供完全的保護。因此,本研究目的為構築一質體嵌入目標基因後建立重組禽痘病毒(fowlpox virus; FPV),藉由同源重組共同表現CIAV VP1及VP2基因,其中,CIAV基因來源為收集自臨床病例,經過選殖及定序決定一株台灣地區野外高致病力分離株。構築一包含thymidine kinase (TK)、green fluorescent protein (GFP)、CIAV VP1及VP2之重組質體,TK基因藉特異限制切位分成兩部分並嵌入pGEX6P-1質體之多重選殖位上,TK基因的上下游位於GFP、CIAV VP1及VP2三種蛋白基因的兩側並嵌入載體以產生pGEX6P-1/TK/GFP/CIAV VP1/VP2重組質體。接著,為產生重組禽痘病毒,將禽痘病毒作為父母代病毒感染於DF1雞纖維母細胞,同時和重組質體進行轉染。父母代禽痘病毒和重組質體成功進行同源重組後可於螢光顯微鏡下看到綠色螢光表現,觀察到第一代重組禽痘毒之產生後,進行間接免疫螢光試驗以確定CIAV蛋白的表現。

Chicken infectious anemia virus (CIAV) is the causative agent of chicken infectious anemia (CIA). CIA distributes globally, affecting all countries and presenting economic threat especially to the broiler industry and the producers of specific-pathogen (SPF) eggs. Though live vaccines are now in use, the recommended age is over 6 weeks of age and can't offer complete protection to young chickens. Thus, the purpose of this study was to construct the plasmid which inserted target genes and developed a recombinant fowlpox virus (rFPV) co-expressing VP1 and VP2 genes of CIAV by homologous recombination. The strain of CIAV was sampled from clinical cases and helped determine a high pathogenicity strain after cloning and sequencing. A recombinant plasmid was constructed with TK, GFP, VP1 and VP2 genes of CIAV. TK gene was separated to 2 segments by specific restriction sites and was inserted into the on multiple cloning sites of the pGEX6P-1 vector. The separated TK gene segments flanked GFP gene, VP1 and VP2 genes of CIAV were inserted in the pGEX6P-1 vector to generate a pGEX6P-1/TK/GFP/CIAV VP1/VP2 recombinant plasmid. Next, to generate rFPV, DF1 cells were infected by FPV as parental FPV and then transfected with recombinant plasmid at the same time. After homologous recombination with parental FPV, green fluorescence could be seen by fluorescence microscope when recombination occurred. After observing the first generation of recombinant fowlpox virus, indirect immunofluorescence assay (IFA) tests were performed to confirm the expression of CIAV proteins.
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