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標題: 微脂粒包覆蠶絲蛋白之製備與功能性評估
The Manufacture and Effectiveness Evaluation of Liposome Incorporated with Silk Protein
作者: Li-Fei Chen
Li-Chou Chen
Chon-Yu Chen
關鍵字: Silk Protein;Liposome;Skin Hydration;Skin Elasticity;蠶絲蛋白;微脂粒;皮膚保濕;皮膚有彈性
出版社: 臺中巿: 國立中興大學農學院
Project: 農林學報, Volume 64, Issue 1, Page(s) 1-10.
This study selected different lipids to prepare silk protein encapsulated liposomes by using ethanol injection method and thin film sonication/ethanol injection method. The prepared formulations also checked with safety test and skin hydration and elasticity. The experimental results showed smaller average particle size about 72~85 nm and better encapsulation rate about 85~90% by using ethanol injection method. For safety test, the sonication/ethanol injection method expressed better particle size stability for both 4℃ and room temperature. For efficacy test, ten different prepared methods and formulations were applied on skin to test skin hydration, elasticity and water content of stratum corneum. Every experimental samples treated 120 min showed better skin hydration than the control sample. After four weeks treatment with inner side of the arm, the skin elasticity also showed obviously improvement. These ten experimental samples also proceed with allergy test for ten people with 48 hours revealed no allergy positive results.

Appears in Collections:第64卷 第01期

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