Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/94794
DC FieldValueLanguage
dc.contributor.authorHuang, Shi-Weizh_TW
dc.contributor.authorChang, Shu-Haozh_TW
dc.contributor.authorMu, Szu-Weizh_TW
dc.contributor.authorJiang, Hsin-Yizh_TW
dc.contributor.authorWang, Sin-Tingzh_TW
dc.contributor.authorKao, Jun-Kaizh_TW
dc.contributor.authorHuang, Jau-Lingzh_TW
dc.contributor.authorWu, Chun-Yingzh_TW
dc.contributor.authorChen, Yi-Juzh_TW
dc.contributor.authorShieh, Jeng-Jerzh_TW
dc.date2016-03-
dc.date.accessioned2018-04-12T03:04:30Z-
dc.date.available2018-04-12T03:04:30Z-
dc.identifier.urihttp://hdl.handle.net/11455/94794-
dc.description.abstractThe tumor suppressor p53 controls DNA repair, cell cycle, apoptosis, autophagy and numerous other cellular processes. Imiquimod (IMQ), a synthetic toll-like receptor (TLR) 7 ligand for the treatment of superficial basal cell carcinoma (BCC), eliminates cancer cells by activating cell-mediated immunity and directly inducing apoptosis and autophagy in cancer cells.zh_TW
dc.language.isoenzh_TW
dc.relationJournal of dermatological science, Volume 81, Issue 3, Page(s) 182-91.zh_TW
dc.subjectApoptosiszh_TW
dc.subjectAutophagyzh_TW
dc.subjectImiquimodzh_TW
dc.subjectp53zh_TW
dc.subjectActive Transport, Cell Nucleuszh_TW
dc.subjectAminoquinolineszh_TW
dc.subjectAntineoplastic Agentszh_TW
dc.subjectApoptosiszh_TW
dc.subjectAtaxia Telangiectasia Mutated Proteinszh_TW
dc.subjectAutophagyzh_TW
dc.subjectCarcinoma, Basal Cellzh_TW
dc.subjectCell Line, Tumorzh_TW
dc.subjectDose-Response Relationship, Drugzh_TW
dc.subjectGene Expression Regulation, Neoplasticzh_TW
dc.subjectHumanszh_TW
dc.subjectMutationzh_TW
dc.subjectPhosphorylationzh_TW
dc.subjectRNA Interferencezh_TW
dc.subjectReactive Oxygen Specieszh_TW
dc.subjectSignal Transductionzh_TW
dc.subjectSkin Neoplasmszh_TW
dc.subjectTime Factorszh_TW
dc.subjectTransfectionzh_TW
dc.subjectTumor Suppressor Protein p53zh_TW
dc.titleImiquimod activates p53-dependent apoptosis in a human basal cell carcinoma cell linezh_TW
dc.typeJournal Articlezh_TW
dc.identifier.doi10.1016/j.jdermsci.2015.12.011zh_TW
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.fulltextno fulltext-
item.languageiso639-1en-
item.grantfulltextnone-
Appears in Collections:生物醫學研究所
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