Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/95842
標題: TPL2 (Therapeutic Targeting Tumor Progression Locus-2)/ATF4 (Activating Transcription Factor-4)/SDF1α (Chemokine Stromal Cell-Derived Factor-α) Axis Suppresses Diabetic Retinopathy
作者: Lai, De-Wei
Lin, Keng-Hung
Sheu, Wayne Huey-Herng
Lee, Maw-Rong
Chen, Chung-Yu
Lee, Wen-Jane
Hung, Yi-Wen
Shen, Chin-Chang
Chung, Tsung-Ju
Liu, Shing-Hwa
許美鈴
Sheu, Meei-Ling
關鍵字: ATF4;ER stress;Nε-(Carboxymethyl)-L-lysine;SDF1α;TPL2;VEGF;diabetic retinopathy;Activating Transcription Factor 4;Animals;Cells, Cultured;Chemokine CXCL12;Diabetes Mellitus, Experimental;Diabetic Retinopathy;Human Umbilical Vein Endothelial Cells;Humans;Lysine;MAP Kinase Kinase Kinases;Mice;Mice, Inbred C57BL;Rats;Rats, Sprague-Dawley;Signal Transduction
出版社: CIRCULATION RESEARCH
Project: Circulation research, Volume 121, Issue 6, Page(s) e37-e52.
摘要: 
Diabetic retinopathy is characterized by vasopermeability, vascular leakage, inflammation, blood-retinal barrier breakdown, capillary degeneration, and neovascularization. However, the mechanisms underlying the association between diabetes mellitus and progression retinopathy remain unclear.
URI: http://hdl.handle.net/11455/95842
DOI: 10.1161/CIRCRESAHA.117.311066
Appears in Collections:生物醫學研究所

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