Please use this identifier to cite or link to this item: http://hdl.handle.net/11455/99353
標題: Antiviral potential of curcumin
作者: Dony Mathew
徐維莉
Wei-Li Hsu
關鍵字: Curcumin;Antiviral;PI3K/Akt;NF-κB;Molecular mechanisms
Project: Journal of Functional Foods, Volume 40, January 2018, Pages 692-699
摘要: 
The use of synthetic drugs has increased over the recent years, but plant-based drugs are more suitable in terms of least side effects. Since ancient times mankind has been dependent on plants for the treatment of various ailments, among them widely used is curcumin, the principal polyphenol extracted from turmeric. Their medicinal and useful properties are mentioned in Indian Veda’s and Chinese medicine. Curcumin has been studied extensively for its pleiotropic activity, including anti-inflammatory, anti-oxidant and anti-tumor activity. Accumulated evidence indicated curcumin plays an inhibitory role against infection of numerous viruses. These mechanisms involve either a direct interference of viral replication machinery or suppression of cellular signaling pathways essential for viral replication, such as PI3K/Akt, NF-κB. This review summarizes the current state of knowledge with a focus on the anti-viral effect of curcumin, and their possible molecular mechanisms.
URI: http://hdl.handle.net/11455/99353
DOI: 10.1016/j.jff.2017.12.017
Appears in Collections:微生物暨公共衛生學研究所

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